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Table 3 Postoperative pain management and adverse events

From: The impact of multimodal analgesia based enhanced recovery protocol on quality of recovery after laparoscopic gynecological surgery: a randomized controlled trial

  Study Group (n = 69) Control Group (n = 69) Median difference (95% CI) P value
NRS scores at PACU admission 1 (1–2.5) 4 (3–5) −3 (−3, − 2) 0.000 *
NRS at 2 h 1 (1–2) 3 (3–3) −2 (− 2, − 2) 0.000 *
NRS at 6 h 1 (1–2) 2 (2–3) −1 (− 2, − 1) 0.000 *
NRS at 24 h 1 (1–1) 2 (1–3) −1 (− 1, − 1) 0.000 *
NRS at 48 h 0 (1–1) 1 (1–1) −1 (− 1, − 1) 0.000 *
Rescue analgesics in PACU (n/%) 4 (5.8) 19 (27.5)   0.0006
Total morphine consumption in PACU (mg) 1 (1–2) 2 (2–4) −1 (− 2, − 1) 0.000 *
Total morphine consumption in 24 h (mg) 2 (1–3.5) 4 (3–7) − 2 (− 3, − 1) 0.000 *
Total morphine consumption in 48 h (mg) 3 (1–4.5) 5 (3–7.5) −2 (− 3, − 1) 0.000 *
PACU sedation (n/%) 5 (7.2) 0   0.068
PONV 0-48 h (n/%) 11 (15.9) 14 (20.3)   0.507
Rescue antiemetics 0-48 h (n/%) 2 (2.9) 2 (2.9)   0.612
Postoperative fever (n/%) 3 (4.3) 5 (7.2)   0.716
Postoperative dizziness (n/%) 8 (11.6) 11 (15.9)   0.459
  1. Data are presented as median (interquartile range)
  2. Abbreviations: NRS Numeric rating scale, PACU Post-anesthesia care unit, PONV Postoperative nausea and vomiting, CI Confidence interval
  3. *P < 0.013, the Mann-Whitney U test with Bonferroni correction