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| |
GDFT group (n = 55)
|
CFT group (n = 57)
|
P
|
|---|
|
Duration of anesthesia (min)
|
254 ± 64.8
|
244 ± 60.6
|
0.413
|
|
Duration of surgery (min)
|
208 ± 59.9
|
200 ± 57.1
|
0.469
|
|
Estimated blood loss (ml)
|
200 (150–300)
|
200 (100–400)
|
0.773
|
|
Total intraoperative fluids (ml)
|
1697 ± 536.9
|
2033 ± 468.7
|
0.001##
|
|
Crystalloid (ml)
|
1111 ± 442.9
|
1411 ± 412.6
|
0.000###
|
|
Colloid (ml)
|
623 ± 211.9
|
586 ± 216.3
|
0.370
|
|
Urine output (ml)
|
200 (150–300)
|
400 (290–500)
|
0.000###
|
|
Intraoperative vasoactive drugs
|
|
Ephedrine
|
25
|
31
|
0.345
|
|
Norepinephrine
|
10
|
4
|
0.091
|
|
Dobutamine
|
9
|
2
|
0.022#
|
|
Nitroglycerin
|
2
|
3
|
1.000
|
|
Lactate (mmol/l)
|
|
T1
|
0.8 (0.6–1.3)
|
0.7 (0.6–0.95)
|
0.363
|
|
T2
|
0.9 (0.6–1.3)
|
0.8 (0.65–1.1)
|
0.243
|
|
T3
|
0.9 (0.7–1.3)
|
1.0 (0.8–1.2) ***
|
0.752
|
- Note: Values are absolute number, mean ± SD (standard deviation) or median (25–75 percentage); *** p < 0.001 analysis of variance (ANOVA) on repeated measurements with Bonferroni correction against baseline; # p < 0.05, ## p < 0.01, ### p < 0.001 analysis of variance by GDFT groups vs CFT group (T-test; Wilcoxon rank-sum tests, or Fisher’s exact tests); T1 5 min prior to induction of anesthesia, T2 60 min after the initiation of surgery, T3 at the end of surgery
