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Table 2 Comparisons of effective concentration of rocuronium

From: Effects of hyperthermia on the effective concentration of rocuronium and sugammadex-mediated reversal in isolated phrenic nerve hemidiaphragm preparations of rats

  36 °C 38 °C 40 °C P-value among all the groups 36 vs. 38 38 vs. 40 36 vs 40
EC5(μg/) 5.3 (1.3)a 4.2 (1.2) 3.1 (1.0)c 0.0014 0.048 0.066 0.0006
EC10 5.8 (1.2) 4.8 (1.2) 3.7 (1.0)c 0.0014 0.056 0.056 0.0006
EC25 6.5 (1.1) 5.6 (1.1)b 4.5 (0.9)c 0.0015 0.087 0.041 0.0006
EC50 7.2 (1.0) 6.4 (1.1)b 5.3 (0.8)c 0.0014 0.115 0.035 0.0005
EC75 7.9 (0.9) 7.2 (1.0)b 6.2 (0.8)c 0.0014 0.167 0.035 0.0004
EC90 8.6 (0.9) 8.0 (1.0)b 7.0 (0.7)c 0.0011 0.131 0.035 0.0003
EC95 9.1 (0.8) 8.5 (1.0)b 7.6 (0.6)c 0.0015 0.167 0.048 0.0003
  1. Values presented as mean (SD). EC, effective concentration
  2. aP value less than 36 °C vs. 38 °C
  3. bP value less than 38 °C vs. 40 °C
  4. CP value less than 36 °C vs. 40 °C